
Mushrooms have been eaten for thousands of years in Asian countries for their health-promoting benefits. More and more research is being conducted to explore the active constituents of certain mushrooms in order to understand their full potential to improve health.
Polysaccharides (a specialized type of carbohydrate) are thought to be the primary active constituents within mushrooms. Researchers believe that mushroom polysaccharide activity results in increased action of specialized immune cells such as natural killer (NK) cells, lymphocyte-activated killer (LAK) cells, lymphocytes, and other subsets.
Mushrooms may also help normalize reduced immune cell counts, such as in patients receiving chemotherapy, and improve immune surveillance, by which NK and LAK cells “seek out and destroy” tumor cells. This may help reduce the risk of cancer in those at high risk or help reduce the risk of cancer recurrence. In addition, specific mushrooms have been shown to tonify, or strengthen, other aspects of bodily function.
Although some of these mushrooms are available in an edible form, the mushrooms introduced below are in a supplement form.
Chaga
Chaga (Inonotus obliquus) has been used for centuries in Siberia and other parts of Asia to boost immunity and improve overall health, energy and endurance. In addition to its potent immune stimulating properties, chaga also provides powerful antioxidant protection. Chaga contains polysaccharide components, as well as betulinic acid, which has been shown to inhibit the growth of colorectal, breast and lung cancer cells.
Cordyceps
Cordyceps (Cordyceps sinensis) mushrooms have a long history of use for helping with aging, boosting strength and reducing fatigue. Research shows that cordyceps may increase energy and endurance, support healthy blood sugar levels, promote a healthy inflammatory response, support liver health, and help the body manage stress.
Usually two species of mushrooms are found in supplements. One is Cordyceps sinensis which is wild and traditionally harvested. The other is Cordyceps militaris which is grown and standardized for its cordycepin content. Both have been researched for energy and performance enhancement.
Reishi
Known as the “mushroom of immortality,” reishi (Ganoderma lucidum) is revered in Traditional Chinese Medicine as a premier adaptogen. Reishi has many health benefits, including supporting a balanced stress response, promoting cardiovascular, liver, and cognitive health, supporting hormone balance, and increasing energy and stamina.
Turkey Tail
Turkey tail (Trametes versicolor) mushroom is one of the best-documented mushrooms in scientific research. It is famous for its role in supporting immune health and has been used for centuries in Traditional Chinese Medicine and Native American herbalism. Turkey tail is rich in nutrients that support the body’s innate immune response, provide powerful antioxidant protection, and nourish beneficial bacteria.
A lot of turkey tail’s credibility is due to its beta-glucans. They are the same polysaccharides studied across medicinal mushrooms for immune modulation. A 2021 review in the journal Molecules on fungal beta-glucans says that these polysaccharides interact with various receptors that regulate the innate immune system. So if you’re wondering what’s the best supplement for immune support that contains medicinal mushrooms, turkey tail is one of the most well-studied places to begin.
Lion’s Mane
Lion’s mane mushroom shows exciting promise for supporting neural and mental health. Research has found that compounds in lion's mane may support the synthesis of nerve growth factors, which are associated with nerve survival and growth. Additional studies show that lion’s mane has the ability to improve cognitive function as well as uplift mood.
Its NGF research has been conducted on lion’s mane due to its fruiting body and mycelium concentrations of hericenones and erinacines. Research has also explored its effects on cognition and mood, which makes it distinct from the other more immunity-related mushrooms above. So if you’re wondering “Are mushrooms good for you?” besides boosting the immune system, lion’s mane is a great example of their potential benefits.
Mushroom Immune Support
Using mushrooms to support a healthy immune response is a tradition that goes back for thousands of years. Our Mushroom Immune Support provides a synergistic blend of nine organic mushrooms (mycelium and fruiting bodies) to provide a full spectrum of myco-nutrients. This powerful formula is designed to maximize the body’s defenses and help the mind and body adapt to physical, mental and environmental stressors.
If you are considering taking mushrooms as part of a cancer protocol, it is strongly advised to consult a licensed naturopathic doctor to determine if mushrooms are an appropriate treatment in your individual case.
For more information on mushrooms and their many uses and benefits, visit Village Green Apothecary.
Frequently Asked Questions
What are medicinal mushrooms used for in immune support?
Mushrooms have long been used to help bolster the immune system primarily via beta-glucans. The body’s immune response relies on polysaccharides to stimulate immune cells such as natural killer (NK) cells and lymphocytes. Popular varieties include turkey tail, reishi and chaga mushrooms. A pharmacist at Village Green can assist you in selecting the best mushroom or combination for you.
Are mushrooms good for health?
Sure! They are low in calories but provide fiber, B vitamins, selenium, and antioxidants. Many also contain beta-glucans, which help stimulate the immune system. In addition, some types of mushrooms have been studied for their potential to support the immune system, memory, and response to stress. Whether you enjoy them on your plate or in a supplement, they may contribute to a well-rounded approach to wellness.
Are Mushrooms Healthy?
Yes, and here’s why. Mushrooms are low-calorie foods that provide fiber, B vitamins, selenium, and antioxidants. Plus, many mushrooms contain beta-glucans, a form of polysaccharide that has been studied as an immune system supporter. Whether on your plate or in a capsule, mushrooms may contribute to a balanced, immune-minded routine.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
References
- Immunomodulating Effects of Fungal Beta-Glucans: From Traditional Use to Medicine
- Medicinal Mushrooms: Past, Present and Future
- Medicinal Mushrooms and Their Use to Strengthen Respiratory Health during and Post-COVID-19 Pandemic
- Subchronic toxicity and genotoxicity studies of Hericium erinaceus beta-glucan extract preparation
- Medicinal Properties and Bioactive Compounds from Wild Mushrooms Native to North America
- Edible mushrooms as an alternative to animal proteins for having a more sustainable diet: a review
- Are mushrooms medicinal?
- Medicinal Mushroom Biotechnology (2024)
- Current Roles of Mushroom in 21st Century Health Sustainability: A Review on Mushroom and Their Roles in Health Sustenance (2026)
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